苯基醚_MSDS化学品安全技术说明书

苯基醚-MSDS化学品安全技术说明书

发表时间：2011-10-31浏览次数：评论：分享：顶：踩：

品名

苯基醚; 氧化二苯; 二苯醚; Phenylether; Diphenyloxide; 1,1-Oxybisbenzene; Diphenyether; CAS：101-84-8

理化性质

有天竺葵样气味的无色液体,挥发性较低。分子式C12-H10-O。分子量170.2。相对密度1.075(20/4℃)。熔点28℃。沸点257.22℃。闪点115℃。自燃点620℃。蒸气密度5.86。蒸气与空气混合物爆炸限0.8～1.5% 。不溶于水; 溶于乙醇、乙醚、苯、冰醋酸。遇热、明火可燃。能与氧化物反应。

接触机会

为氯苯法制造酚时的副产品。用作热载体。制造表面活性剂和高温润滑剂的原料。也用在香料中。由于其蒸气压低,在室温下很少有可能吸入较高浓度的蒸气。

国内主要生产厂商:苏州溶剂厂、上海香料厂、上海香料二厂

侵入途径

可经消化道吸收。

毒理学简介

大鼠经口LD50: 2450 mg/kg。兔经皮LD50: >7940 mg/kg。

口服毒性低。对皮肤刺激不明显。其难闻的气味可令人感到恶心。给豚鼠1g/kg及大鼠2g/kg灌胃,动物全部存活,解剖可见肝、脾、肾、甲状腺、肠道有损害。

人嗅觉阈浓度为0.008mg/m^3。

IDLH: +100 ppm [R22]

临床表现

未见急性中毒报道。

美国HSDB引用文献：

*IT IS ONLY SLIGHTLY IRRITATING TO SKIN AND OCCASIONAL BRIEF CONTACT DOES NOT HAVE ANY EFFECT. IRRITATION OCCURS ONLY AFTER REPEATED & PROLONGED CONTACT. ODOR IS EXTREMELY UNPLEASANT. [R8]

*AT CONCN OF 7-10 PPM /OF DOWTHERM/, VAPOR CAUSES BURNING OF EYES, IRRITATION OF RESPIRATORY TRACT & SEVERE NAUSEA. REPEATED & PROLONGED CONTACT CAN CAUSE IRRITATION OF SKIN. /DOWTHERM/ [R8]

*ACUTE INTOXICATION /BY DOWTHERM/ IS POSSIBLE FROM ACCIDENTAL INGESTION, RESULTING IN SEVERE DEGENERATIVE LESIONS IN LIVER & KIDNEYS, WHICH ARE IRREVERSIBLE IF DOSE IS VERY LARGE. /DOWTHERM/ [R8]

*... DOES NOT PRESENT AN APPRECIABLE HAZARD TO HEALTH AS ORDINARILY USED. [R24, 2542]

*... VAPOR CONCN THAT CAN OCCUR AT ORDINARY ROOM TEMP PRESENT NO HAZARD OF SYSTEMIC INJURY. ... CONC ARE QUITE LOW BECAUSE OF THE LOWER VAPOR PRESSURE OF THE MATERIAL ... /AND/ SUCH CONC HAVE AN ODOR WHICH MAY BE DISAGREEABLE. [R24, 2542]

处理

对症处理。

标准

车间空气卫生标准:

美国ACGIH TLV-STEL 14 mg/m3 (2 ppm)

美国ACGIH TLV-TWA 7 mg/m3 (1 ppm)

美国MSHA STANDARD-air: TWA 1 ppm (7 mg/m3) (蒸汽)

美国OSHA PEL(所有行业): 8H TWA 1 ppm (7 mg/m3), 蒸汽

澳大利亚: TWA 1 ppm (7 mg/m3), STEL 2 ppm (14 mg/m3)

奥地利: TWA 1 ppm (7 mg/m3)

比利时: TWA 1 ppm (7 mg/m3), STEL 2 ppm (14 mg/m3)

丹麦: TWA 1 ppm (7 mg/m3)