品名

三烯丙胺; Triallylamine; CAS：102-70-5

理化性质

有不快臭味的液体。分子式C9-H15-N。化学式(CH2=CHCH2)3N。分子量137.22。相对密度0.8(20/4℃)。熔点<-70℃。沸点150～151℃。闪点39.44℃(开杯)。蒸气密度4.73。水中溶解度0.25g/100ml; 溶于乙醇、乙醚、丙酮和苯。遇热、明火、氧化剂易燃。加热分解,生成氮氧化物。

接触机会

系有机合成中间体。

侵入途径

可经呼吸道、消化道和皮肤吸收。

毒理学简介

人（男性）吸入TCLo: 13 ppm/5M。

大鼠经口LD50: 1030 mg/kg; 吸入LC50: 554 ppm/8H。小鼠经口LD50: 492 mg/kg。兔经皮LD50: 400 uL/kg。

人在0.5ppm浓度下可闻及臭味。本品吸入毒性比一烯丙胺为弱,经口、经皮毒性比一烯丙胺与二烯丙胺为弱。对皮肤、粘膜具弱刺激作用。

临床表现

人在12.5ppm出现胸部不适与粘膜刺激症状,到50ppm时症状加剧,75～100ppm时粘膜刺激症状更见加重,伴恶心、眩晕、头痛等全身症状。

美国HSDB引用文献：

*TRIALLYL AMINE /VAPORS ON HUMAN SUBJECTS/ @ 0.5 PPM HAD NOTICEABLE BUT MUSTY RATHER THAN OFFENSIVE ODOR. AT 50 TO 100 PPM IT CAUSED INCREASING IRRITATION, COUGHING... [R7]

*IN GENERAL ALLYL AMINES IRRITATED NOSE & THROAT @ LOWER CONCN THAN WERE IRRITANT TO EYES. VAPORS ARE SO UNPLEASANT THAT IT IS UNLIKELY HUMAN BEINGS WOULD VOLUNTARILY SUBMIT TO SYSTEMICALLY DANGEROUS CONCN. /ALLYL AMINES/ [R7]

*...PROBABLY TOXIC & IRRITANT. [R4]

*UNLIKE SATURATED LOWER ALKYLAMINES, SECONDARY & TERTIARY ALLYLAMINES ARE LESS TOXIC THAN MONOALLYLAMINE. ...DECR ACUTE ORAL & PERCUTANEOUS TOXICITY FROM MONO-ALLYLAMINE TO TRIALLYLAMINE...TRIALLYLAMINE SHOWED INCR RELATIVE TOXICITY AS COMPARED TO DIALLYLAMINE ON INHALATION. [R6, 2056]

处理

对症治疗。

标准

危规：GB3.3类33622。原铁规:有机有毒品,84244。UN NO.2610。IMDG CODE 3156-1页,3.3类。

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