品名

四氢呋喃醇; Tetrahydrofurfuryl alcohol; CAS:97-99-4

理化性质

为无色液体。分子式C5-H10-O2。分子量102.15。沸点178℃。相对密度1.0543 。蒸汽密度3.5 g/l。能与水和多种有机溶剂混溶。

接触机会

在作树脂、染料的溶剂时接触本品。

侵入途径

经呼吸道和消化道侵入机体。

毒理学简介

大鼠经口LD50: 1600 mg/kg。小鼠经口LD50: 2300 mg/kg。

属低毒类。

临床表现

对皮肤、眼和粘膜有中度刺激。有急性中毒后死亡的报告。

美国HSDB引用文献：

*EFFECTS REPORTED IN ACUTE POISONING WHICH RESULTED IN DEATH WITHIN 2-3 DAYS WERE SWELLING IN THE BRAIN, HEMORRHAGES IN VISCERAL PLEURA & EPICARDIUM, HYPERVOLEMIA OF ORGANS, & EXPANDED LUNG. MUCOSA OF THE UPPER DIGESTIVE TRACT & STOMACH SHOWED SWELLING, HYPERVOLEMIA, HEMORRHAGE, & NECROSIS. IN DEATH OCCURRING AFTER 3 DAYS, LIVER WEIGHT INCREASED & SHOWED YELLOWISH-BROWN CROSS SECTION WITH HEMORRHAGES. HEPATOCYTES WERE NECROTIC & SOME CONTAINED FAT DROPLETS. [R13]

处理

冲洗眼和污染的皮肤。吸入时给氧，对症治疗。

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